Question 1: In hemolytic anemia, jaundice occurs only when:

• Heme destruction exceeds the liver’s ability to conjugate and excrete bilirubin. (correct answer)
• Erythrocytes are destroyed in the spleen.
• The patient has elevations in aspartate transaminase (AST) and alanine transaminase (ALT).
• The erythrocytes are coated with an immunoglobulin. Instructor Explanation: Jaundice (icterus) is present when heme destruction exceeds the liver’s ability to conjugate and excrete bilirubin.

Points Received: 2 of 2 Comments:

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Question 2: Which anemia produces small, pale erythrocytes?

• Iron deficiency (correct answer)
• (Other answer options not provided) Points Received: 2 of 2 Comments:

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Question 3: Untreated pernicious anemia is fatal, usually because of

• (Answer not provided, please unlock and enrich the document for the correct answer)

Points Received: 2 of 2 Comments:

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Question 4: Clinical manifestations of mild to moderate splenomegaly and hepatomegaly, bronze-colored skin, and cardiac dysrhythmias are indicative of which anemia?

• Iron deficiency
• Pernicious
• Sideroblastic (correct answer)
• Aplastic Instructor Explanation: Mild to moderate enlargement of the spleen (splenomegaly) and liver (hepatomegaly) occurs. Occasionally, abnormal skin pigmentation (bronze-colored) is seen. Heart rhythm disturbances, along with congestive heart failure, are major life-threatening complications related to cardiac iron overload.

Points Received: 2 of 2 Comments:

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Question 5: Pernicious anemia generally requires continued therapy lasting:

• 8 to 12 months.
• Until the iron level is normal.
• The rest of one’s life. (correct answer) Instructor Explanation: Pernicious anemia cannot be cured, so maintenance therapy is lifelong.

Points Received: 2 of 2 Comments:

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Question 6: The underlying disorder of _____ anemia is defective secretion of intrinsic factor, which is essential for the absorption of vitamin B12.

• (Answer not provided, please unlock and enrich the document for the correct answer)

Points Received: 2 of 2 Comments:

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Question 3: Untreated pernicious anemia is fatal, usually because of:

• Heart failure (correct answer) Explanation: Untreated pernicious anemia can be fatal, primarily due to complications such as heart failure, which arises from the severe anemia and its effects on the cardiovascular system.

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Question 6: The underlying disorder of _____ anemia is defective secretion of intrinsic factor, which is essential for the absorption of vitamin B12.

• Pernicious anemia (correct answer) Explanation: Pernicious anemia is caused by the defective secretion of intrinsic factor by the stomach’s parietal cells, which is necessary for the absorption of vitamin B12 in the small intestine.